Show Closed This production ended its run on Feb. 14, 2016 View Comments Oh my! George Takei, Lea Salonga, Telly Leung and the company of Allegiance will head to the studio to record a cast album on December 7. Produced by Lynne Shankel and Joel Moss, the album is scheduled to be released digitally on January 30, 2016.Directed by Stafford Arima and based on Takei’s childhood experience in a Japanese-American interment camp, Allegiance features music and lyrics by Jay Kuo and a book by Marc Acito. A story of family, love and patriotism set during World War II and beyond, the show follows veteran Sam Otsuka and his sister Kei as they find themselves torn between loyalty to their family and allegiance to their country.The cast also includes Katie Rose Clarke, Michael K. Lee, Christopheren Nomura and Greg Watanabe.Allegiance is running at the Longacre Theatre. Related Shows Allegiance
For more than 40 years, Bisphenol A, more commonly known as BPA, was used in everything from plastic baby bottles and the lining of metal food containers to dental sealants. When scientists began seeing a connection between BPA and abnormal sperm and egg development, it set off worldwide public health concerns. The types of abnormal development researchers detected could lead to increased cases of Downs and Klinefelter syndromes in children or to infertility.As more scientists began investigating the effects of toxicant exposure and links to abnormal fetal development, three University of Georgia researchers discovered a more efficient, accurate and cost-effective way to conduct these studies using cells in a petri dish. Franklin West and Steve Stice, animal scientists in the UGA College of Agricultural and Environmental Sciences, and Mary Alice Smith, a toxicologist in environmental health science in the UGA College of Public Health, began testing the efficiency of a technology West and Stice developed to measure the effects of environmental toxicants. They use cells that come from stem cells and represent the early cells that eventually will form sperm cells in adults. The cells are highly vulnerable to toxicants.Their findings were published recently in Toxicological Sciences.“There is no human system to study toxicant effects on early sperm development,” West said. “But, we can expose these human cells to different toxicants and predict how changes will impact birth defects and fertility later in life.”Currently, most developmental toxicological studies are done using mice or rats. “We need to move away from rodent tests because they often won’t tell us how detrimental or safe chemicals are in humans,” West said. “For example, the potential effects of BPA in humans, especially in the unborn child, is still hotly contested. This cell culture system moves us away from animal testing, which most agree is preferable as long as the studies are equally or more reliable.”The new testing model fills a void left by current methods and provides human-specific results.“Using animal studies, you are looking at more than a year to test a chemical in rodents,” Stice said. “Using this test, we get results in two to three weeks at most and possibly shorter.”Considering the vast number of untested chemicals humans are exposed to, with new ones coming out every day, animal testing will never be practical to prioritize which chemicals need further testing, Stice said. There are more than 80,000 chemicals in the environment that haven’t been tested for human impact mainly because of the cost and time required using current procedures.The reliability of those results also must be considered.“Mice don’t have three or four (of the) critically important genes that are leading causes of infertility,” West explained. “Sperm and egg cells are the only cells that go through meiosis, a special type of cell division necessary for sexual reproduction. You can’t use another type of cell to find the impact a chemical has on these cells and, in turn, fetal development.”West first developed the germ-like cells during his doctoral work in Stice’s UGA laboratory.“Our next step with the cells is to test more chemicals and see what happens with more compounds,” he said.Stice also plans to use neural and bone forming cells he developed to test chemicals for developmental neurological and skeletal toxicology. Scientists at the Environmental Protection Agency already have demonstrated in peer-reviewed studies that these types of cells are very sensitive to known toxins such as lead and mercury. The team is now testing more chemicals on these cells.“If the assay is predictive and repeatable, the chemical industry will have better, faster and less expensive test systems and, as a result, will reduce the use of animal testing and experiments,” Stice said.“Testing more known chemicals for developmental toxicology will validate these assays for later use by the chemical industry. Our shared long-term goal is to ensure the health and well being of our children,” he said.An abstract of the journal article is available at http://toxsci.oxfordjournals.org/content/129/1/9.
By Dialogo April 15, 2011 An operation by the Special Operations Battalion (BOPE) in two slums in northern Rio de Janeiro on 13 April left five dead, believed to be drug traffickers, a Military Police spokesperson informed AFP. The operation to suppress drug trafficking and weapons trafficking in the slums of Manguinhos and Mandela mobilized one hundred police officers, supported by two armored vehicles. Three pistols, two grenades, twenty-three motorcycles, and chemical substances for manufacturing drugs were confiscated, the police specified, and four arrests were made. Elsewhere, in western Rio, the Civil Police carried out an operation on 13 April to dismantle a police-style militia suspected of operating in thirteen slums. A city councilor was arrested, and fourteen arrest warrants were issued by the judicial authorities. The expansion of militias in Rio de Janeiro goes back to 2006, when groups of active or retired police officers invaded several favelas in the western part of the city, expelled drug traffickers, and started to collect “security fees” from inhabitants. Militias are present in 105 of the city’s 250 major slums, according to a report by Paulo Storani, a former captain of the elite Special Operations Unit (BOPE) of the Military Police. The authorities of Rio de Janeiro state, one of the country’s most violent, began a countercampaign in 2008 to pacify the city and eliminate militias and drug traffickers from the slums, ahead of hosting the World Cup in 2014 and the Olympics in 2016. At present, around twenty slums have been pacified.
NBA trade deadline: 76ers send Markelle Fultz to Magic for Jonathon Simmons, draft picks Wishing you the best, Enes. pic.twitter.com/OajT463n3V— NEW YORK KNICKS (@nyknicks) February 7, 2019The Knicks have been trying to move Kanter for a few weeks, but his contract made things difficult, according to the initial report by ESPN. Kanter has an $18.6 million expiring deal.Kanter recently said he was unhappy with his smaller role with the team and that he’s “very disappointed” with coach David Fitzdale’s decision to keep him out of the rotation. Related News Enes Kanter’s time with the Knicks has come to a close.New York released the center Thursday, shortly after the NBA’s trade deadline had passed. Kanter appeared in just three of the Knicks’ last 12 games. One of the main reasons is the Knicks are trying to develop their younger players while also utilizing DeAndre Jordan, who New York acquired in a blockbuster trade with the Mavericks that sent Kristaps Porzingis to Dallas. NBA trade deadline: Grizzlies acquire Avery Bradley from Clippers for two players The Knicks’ abysmal record (10-43), along with the talk of releasing Kanter, had prompted fans at some home games to chant “We want Kanter!””I don’t know if the organization wants to hear that every game because it’s a little embarrassing,” Kanter said recently of the chants. “Because after all this [Porzingis] trade and everything that the fans still want me to go out there and play. I don’t know if they wanna hear that chant every game.”Kanter is averaging 14 points and 10 rebounds in 26 minutes per game this season.