Tag: 杭州夜网

The listing of this home at Hamilton is tipped to test the luxury market

first_img1 Dickson Tce, Hamilton. 1 Dickson Tce, Hamilton.BRISBANE’S high end property market has been firing of late, with a number of significant multimillion-dollar sales chalked up in recent weeks.Nationally, million dollar plus sales are rising with the latest figures revealing the number of properties selling for more than $1 million is at a new record high.In the 12 months to June 2017, 15.4 per cent of all house sales and 8.8 per cent of all unit sales nationally were at a price of at least $1 million.A property predicted to well and truly exceed that level is a home owned by Brisbane developer Anthony Barakat and his wife Terrie at Hamilton.Mr Barakat, who does a lot of his investing south of the border these days, said with their four children growing up, they didn’t use the home at 1 Dickson Tce, as much as they once did and they were going to downsize to a unit.1 Dickson Tce, Hamilton.More from newsMould, age, not enough to stop 17 bidders fighting for this home2 hours agoBuyers ‘crazy’ not to take govt freebies, says 28-yr-old investor2 hours agoThe house at 1 Dickson Tce, Hamilton was designed by Greg Harris who also designed a massive home at 1 Leopard St, Kangaroo Point which broke Brisbane’s house price record when it sold for more than $18 million earlier this year.1 Dickson Tce, Hamilton.Mr Barakat said as his children grew older they really only used three rooms of the house, the kitchen, the laundry (which was in constant use) and the barbecue area.1 Dickson Tce, Hamilton.The home has multiple living and entertainment areas over three levels. There is an infinity edge pool with glass fencing and an outdoor kitchen.1 Dickson Tce, Hamilton.The home has been listed through Damon Warat of Ray White Ascot.1 Dickson Tce, Hamilton.last_img read more

Cardiff lose appeal against Joe Ralls red card at Tottenham

first_img Every time Ally McCoist lost it on air in 2019, including funny XI reactions silverware Where Ancelotti ranks with every Premier League boss for trophies won The Bluebirds challenged the red card, but their appeal has been rejected by the Football Association.After the game, Cardiff manager Neil Warnock branded the decision as “very soft” and accused Spurs striker Harry Kane of “trying to make an issue of it” by squaring up to Ralls. 2 Ronaldo warned Lukaku how hard scoring goals in Serie A would be before Inter move Oxlade-Chamberlain suffers another setback as Klopp confirms serious injury England’s most successful clubs of the past decade, according to trophies won ADVICE REVEALED LATEST FOOTBALL NEWS Cardiff have lost their appeal against Joe Ralls’ red card at Tottenham.Ralls was sent off by referee Mike Dean for a 58th-minute tackle on Lucas Moura in Saturday’s 1-0 Premier League defeat at Wembley. MONEY center_img Top nine Premier League free transfers of the decade REVEALED Which teams do the best on Boxing Day in the Premier League era? Kane reacted furiously to the challenge “You don’t go off like that. He (Kane) is doing that to make an issue of it, to get the referee thinking (it was) worse than what it is,” Warnock said.“I don’t think you should try to get other pros sent off, just because he’s had a poor game and Spurs were having a poor game. He shouldn’t take it out on us.”Ralls will now serve a three-game ban and miss matches against Fulham, Liverpool and Leicester. Forbes list reveals how much Mayweather, Ronaldo and Messi earned this decade BEST OF Ralls will serve a three-match ban huge blow RANKED 2last_img read more

17 Ways to Hide a Lavalier Mic

first_imgThe latest video from Aputure offers an extremely fun and helpful tutorial on how to properly mic up wildly different costumes.Recording good, clean audio is one of the hardest things to do in filmmaking. Setting a lavalier microphone on a bulky, scratchy, or nonexistent costume is one of the trickiest feats out there. Luckily, this in-depth tutorial from Aputure gives us everything we need to know (like the best gear to use), plus some handy examples and extremely helpful advice.We recommend checking out Aputure’s YouTube channel for more helpful content with production and filmmaking.Major HighlightsImage via AputureTed Sim and Stephen Harrod discuss some of the many ways to efficiently mic your subject, regardless of their costume, and cover the challenges of working with latex, chain — and no costume at all. Harrod lists several different items available to help conceal and secure your lav, items that are easy to find and very affordable. For example:Moleskin PlusThis Dr. Scholl’s product is cheap and helps create separation between costume and microphone, avoiding that muffled scratchy sound you’ve inevitably picked up before.Vapon TopstickFor sticking the mic securely on the talent, Harrod recommends this easy-to-use pain-free adhesive.Rycoat OvercoversThis tiny dead cat is perfect for preventing rustles and scratches from clothing. These are crucial when the talent is wearing multiple layers of clothing.Helpful HintsImage via AputureHiding in the HairWorking with spaghetti straps and tank tops can be a challenge. Harrod suggests trying to hide the mic on the sternum or in the cleavage. And if that doesn’t work? Try hiding the mic in the hairline!Dress ShirtsTaping the mic on the sternum, in between the buttons of the shirt, should guarantee security and quality audio. However, if a tie is being worn, consider placing the mic in the knot of the tie instead of on the sternum.Sew the Mic InFor narrative endeavors, never rule out extensive pre-production with your costumes. Harrod dives into the possibilities of sewing the mic into the fabric and how beneficial this strategy can be.Helmets GaloreThough it might seem obvious, anytime a subject wears a helmet, you’ve got a clear shot for good audio. The helmet will provide a great place to attach our mic with little to no chance of being seen.Ditching the LavIt’s inevitable. Sometimes wardrobe and audio just aren’t going to work well together. When in doubt, get the boom out.Consider the CameraThis might seem like the most obvious hint, but always mind the camera’s blocking and position at all times. A receiver sticking out at the bottom of the screen is never a good look.Combinations CoveredImage via AputureYou might not encounter some of the big-budget challenges Harrod covers in the video, but his advice is crucial for approaching difficult situations. From leather cowboy garb and chain-mail armor, to Batsuits and birthday suits, a reasonable lavalier solution can be found.Know of any other sneaky spots to hide the mic? Let us know in the comments!last_img read more

Hamstring injury sidelines San Miguel’s Alex Cabagnot

first_imgPrivate companies step in to help SEA Games hosting Oil plant explodes in Pampanga town “It was a good response by the team, but we’re just at 1-1 so we shouldn’t celebrate,” said Cabagnot. “We should be as level headed as possible because the season is far from over and the conference has just started.”“We have to work hard and do the things we need to do.”Sports Related Videospowered by AdSparcRead Next Despite herculean effort, Moala Tautuaa knows he needs to work harder to stay course ‘We are too hospitable,’ says Sotto amid SEA Games woes LATEST STORIES SEA Games hosting troubles anger Duterte Lacson backs proposal to elect president and vice president in tandem Don’t miss out on the latest news and information. MANILA, Philippines—San Miguel point guard Alex Cabagnot is out indefinitely after suffering a hamstring injury in the Beermen’s previous game in the PBA Philippine Cup against Columbian.Cabagnot said on Sunday that his left hamstring has been bothering him for a couple of weeks and it only got worse in the Beermen’s 124-118 loss to the Dyip on Friday.ADVERTISEMENT “I hurt my hamstring last game when I dove on the floor but we were trying to catch up so you have to try anything to win the game,” said Cabagnot after the Beermen’s recent 99-91 win over Barangay Ginebra at Smart Araneta Coliseum.“Whatever happens I just did what I had to do and the worst consequence was I hurt my hamstring and that has been bothering me for the past two weeks, hopefully and God willing I’ll be back soon.”FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSUrgent reply from Philippine ‍football chiefSPORTSWin or don’t eat: the Philippines’ poverty-driven, world-beating pool starsCabagnot sat out the game against the Gin Kings in what he described as a great bounce back win for the Beermen.The 36-year-old Cabagnot didn’t sit with the team on the bench and instead joined the team officials a little further up behind the Beermen to better get a view of the action. US judge bars Trump’s health insurance rule for immigrants MOST READ PH underwater hockey team aims to make waves in SEA Games PLAY LIST 02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss Grace Poe files bill to protect govt teachers from malicious accusations Oil plant explodes in Pampanga town View commentslast_img read more

Rep Maturen hosts family of fallen first responder for Sept 11 Memorial

first_img07Sep Rep. Maturen hosts family of fallen first responder for Sept. 11 Memorial Service Categories: Maturen News,News State Rep. David Maturen today took part in the annual House ceremony recognizing first responders and members of the military who died in the line of duty during the past year.Maturen, of Vicksburg, read the names of Wayne State University K9 Officer Collin Rose, who was shot and killed on Nov. 22, 2016, and Comstock Township Fire Chief Edward Switalski, who died in the line of duty on June 13 of this year. Maturen also invited relatives of the two men, who lived in the communities he represents, to attend the ceremony.“The terrorist attacks of Sept. 11, 2001, demonstrated the heroic lengths first responders and members of the military went to attempting to save the lives of people in the World Trade Center and the Pentagon,” Maturen said. “We conduct this ceremony at the Capitol every year so we can honor the heroes from our communities who put their lives on the line every day they go to work. It helps provide comfort to family members to know the sacrifice their spouse, children or parents made is not forgotten.”The House has conducted the ceremony since September 2011, the 10th anniversary of the terrorist attacks.PHOTO INFORMATION: State Rep. David Maturen, of Vicksburg, was joined today by Randy and Karen Rose, parents of fallen Wayne State University K9 Officer Collin Rose, and Collin Rose’s fiancé, Nikki Salgot, as his guests for the Michigan House’s annual Sept. 11 Memorial Service at the Capitol. The ceremony remembers first responders and members of the military from Michigan who died in the line of duty in the past year.last_img read more

Polygenic screening could inform breast cancer risk in female survivors of pediatric

first_img Source:http://www.aacr.org/ Reviewed by James Ives, M.Psych. (Editor)Oct 26 2018Bottom Line: A combined evaluation of common variants with small effects and rare predisposing mutations among young female childhood cancer survivors may further stratify this high-risk population for subsequent breast cancer risk.Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer ResearchAuthor: Zhaoming Wang, PhD, associate member in the Department of Epidemiology and Cancer Control at the St. Jude Children’s Research Hospital in MemphisBackground: Female childhood cancer survivors have an increased risk of developing subsequent breast cancer compared with the general population. This increased risk has largely been attributed to cancer treatment regimens, such as chest irradiation and/or exposure to high-dose chemotherapeutic agents. Current screening of this population relies on treatments and doses used to treat childhood cancer, Wang explained.Wang previously found that survivors of childhood cancer have an increased risk of subsequent breast cancer if the survivors carry pathogenic or likely pathogenic (P/LP) mutations, such as mutations to the BRCA1 gene. “Our current study attempts to investigate the contributions to the risk of subsequent breast cancer by considering the full picture of breast cancer genetic susceptibility, which includes common genetic variants with small effects (polygenic determinants) in addition to P/LP mutations (monogenic determinants),” said Wang.How the Study Was Conducted: Wang and colleagues utilized information from the St. Jude Lifetime Cohort Study (SJLIFE) by analyzing whole-genome sequencing data for 1,133 female cancer survivors of European ancestry. Of these survivors, 47 developed one or more subsequent breast cancers.The researchers constructed a polygenic risk score (PRS) for individual survivors by calculating the weighted sum of 170 common breast cancer risk alleles present in each survivor’s genome. The researchers also evaluated the presence of P/LP mutations in 11 breast cancer predisposition genes. Relative rates of subsequent breast cancer incidence were estimated.Results: Following multivariable analysis, the researchers found that survivors in the highest PRS quintile had 2.7 times the risk of subsequent breast cancer compared to survivors in the lowest quintile. Survivors treated with chest irradiation had even higher risk; those in the highest PRS quintile treated with radiation had three times the risk of subsequent cancer compared to those in lowest quintile treated with radiation.Related StoriesCancer killing capability of lesser-known immune cells identifiedHow cell-free DNA can be targeted to prevent spread of tumorsHealthy lifestyle lowers dementia risk despite genetic predispositionSurvivors who carried P/LP mutations had 21.8 times increased risk for subsequent breast cancer compared with those who didn’t have P/LP mutations. Survivors treated with chest irradiation and who carried P/LP mutations had 10.3 times increased risk for subsequent breast cancer compared with those who didn’t have P/LP mutations treated with chest irradiation.”The PRS can identify individuals with high breast cancer risk that do not carry known pathogenic mutations,” Wang said. “Our results indicate that both polygenic determinants and large-effect rare mutations (monogenic determinants) contribute to the risk of subsequent breast cancer independently.”Notably, PRS was significantly associated with risk of subsequent breast cancer only in women less than 45 years old.”Our data supports the hypothesis that genetic risk factors play a more important role in the development of subsequent breast cancers in younger women,” Wang said. “However, this observed age-specific association could be partly due to the smaller sample size of older survivors in our study.”P/LP mutations were defined as mutations to the following breast cancer predisposition genes: BRCA1, BRCA2, TP53, PTEN, CDH1, STK11, NF1, PALB2, ATM, CHEK2, and NBN.Author’s Comments: “Our findings suggest that polygenic screening can inform personalized breast cancer surveillance in female childhood cancer survivors,” said Wang. “This method can be utilized in the clinical setting to enhance the identification of high-risk survivors to enable the early detection and potential prevention of subsequent breast cancer.”Wang also said, “Our results indicate that personalized breast cancer surveillance strategies for survivors should incorporate prior exposure to specific anti-cancer treatments, the presence of P/LP mutations, and the cumulative presence of small-effect common variants, as represented by a polygenic risk score.”Study Limitations: Limitations of the study include a relatively young cohort of childhood cancer survivors. Additionally, analysis was restricted to survivors of European ancestry; follow-up studies should be conducted within other non-European ethnic groups.last_img read more

Research shows possibility to shift the circadian rhythm of night owls

first_img Wake up 2-3 hours before regular wake up time and maximise outdoor light during the mornings. Go to bed 2-3 hours before habitual bedtime and limit light exposure in the evening. Keep sleep/wake times fixed on both work days and free days. Have breakfast as soon as possible after waking up, eat lunch at the same time each day, and refrain from eating dinner after 7pm. Establishing simple routines could help ‘night owls’ adjust their body clocks and improve their overall physical and mental health. Insufficient levels of sleep and circadian misalignment can disrupt many bodily processes putting us at increased risk of cardiovascular disease, cancer and diabetes.”Professor Debra Skene from the University of Surrey Having a late sleep pattern puts you at odds with the standard societal days, which can lead to a range of adverse outcomes – from daytime sleepiness to poorer mental wellbeing.”Co-author Dr Andrew Bagshaw from the University of Birmingham “We wanted to see if there were simple things people could do at home to solve this issue. This was successful, on average allowing people to get to sleep and wake up around two hours earlier than they were before. Most interestingly, this was also associated with improvements in mental wellbeing and perceived sleepiness, meaning that it was a very positive outcome for the participants. We now need to understand how habitual sleep patterns are related to the brain, how this links with mental wellbeing and whether the interventions lead to long-term changes.”Related StoriesResearch sheds light on sun-induced DNA damage and repairNew therapy shows promise in preventing brain damage after traumatic brain injuryRush University Medical Center offers new FDA-approved treatment for brain aneurysmsTwenty-two healthy individuals participated in the study. For a period of three weeks participants in the experimental group were asked to: The results highlighted an increase in cognitive (reaction time) and physical (grip strength) performance during the morning when tiredness is often very high in ‘night owls’, as well as a shift in peak performance times from evening to afternoon. It also increased the number of days in which breakfast was consumed and led to better mental well-being, with participants reporting a decrease in feelings of stress and depression. Reviewed by James Ives, M.Psych. (Editor)Jun 10 2019A simple tweak to the sleeping patterns of ‘night owls’ – people with extreme late sleeping and waking habits – could lead to significant improvements in sleep/wake timings, improved performance in the mornings, better eating habits and a decrease in depression and stress.New international research by the Universities of Birmingham and Surrey in the UK, and Monash University in Australia, showed that, over a three-week period, it was possible to shift the circadian rhythm of ‘night owls’ using non-pharmacological and practical interventions.The study, published in Sleep Medicine, showed participants were able to bring forward their sleep/wake timings by two hours, while having no negative effect on sleep duration. In addition, participants reported a decrease in feelings of depression and stress, as well as in daytime sleepiness.”Our research findings highlight the ability of a simple non-pharmacological intervention to phase advance ‘night owls’, reduce negative elements of mental health and sleepiness, as well as manipulate peak performance times in the real world,” lead researcher Dr Elise Facer-Childs from Monash University’s Turner Institute for Brain and Mental Health said.’Night owls’ are individuals whose internal body clock dictates later-than-usual sleep and wake times – in this study participants had an average bedtime of 2.30am and wake-up time of 10.15am.Disturbances to the sleep/wake system have been linked to a variety of health issues, including mood swings, increased morbidity and mortality rates, and declines in cognitive and physical performance. Dr Facer-Childs said ‘night owls’, compared to ‘morning larks’, tended to be more compromised in our society due to having to fit to work/school schedules that are out of sync with their preferred patterns.”By acknowledging these differences and providing tools to improve outcomes we can go a long way in a society that is under constant pressure to achieve optimal productivity and performance,” she said.This intervention could also be applied within more niche settings, such as industry or within sporting sectors, which have a key focus on developing strategies to maximize productivity and optimize performance at certain times and in different conditions.Source: University of Birminghamlast_img read more

Research team receives federal grant to study obesity in children with spina

first_imgChildren with spina bifida are known to have a decreased level of energy expenditure, although we cannot specify how much less as compared to their typically developing peers. Our hypothesis is that the number of calories we currently recommend parents feed their children may be higher than it should be, inadvertently contributing to excess weight gain.”Michele Polfuss, Joint Research Chair in the Nursing of Children at the University of Wisconsin-Milwaukee and Children’s Hospital of Wisconsin Reviewed by Alina Shrourou, B.Sc. (Editor)Jul 10 2019Children with spina bifida, a congenital condition of the spine and spinal cord, have a higher rate of obesity compared to typically developing peers. One barrier to better prevention of obesity is accurately assessing body fat.Michele Polfuss is leading a research team in a $3.6 million federal grant to investigate methods of accurately measuring patients’ body composition in a clinical setting.Polfuss is the Joint Research Chair in the Nursing of Children at the University of Wisconsin-Milwaukee and Children’s Hospital of Wisconsin. With an interdisciplinary team of professionals, she will determine methods of providing information on the amount of energy expended or calories used in children with spina bifida and determine an accurate assessment of their weight category. For people who are not disabled, health providers can get a fairly accurate assessment of a person’s weight status by measuring the person’s height and weight, and then using this information to calculate a body mass index. That doesn’t work well for children with spina bifida who may be unable to stand or have orthopedic complications that challenge their ability to have an accurate measure of height or weight performed, said Polfuss. If the measure of height or weight is not accurate, then the BMI is inaccurate.Related StoriesNew therapeutic food boosts key growth-promoting gut microbes in malnourished childrenUCR biomedical professor to investigate how body’s cannabis-like molecules influence obesityDaily intake for phosphates in infants, children can exceed health guidance valuesThe aim of the project is twofold, said Polfuss. “We want to find a feasible method of measuring body fat that can be conducted cost-effectively and accurately in the clinic – and to provide better guidance to the family on nutritional intake recommendations, with the ultimate goal of preventing and treating obesity.”The project team includes health professionals from four pediatric spina bifida programs at children’s hospitals across the United States – Children’s Hospital of Wisconsin, Children’s Hospital of Los Angeles, Children’s Hospital of Alabama-Birmingham and Children’s Hospital of Pittsburgh – who are working with 232 children.”We are happy to help lead the effort on this important and needed research,” said Nancy Korom, chief nursing officer and vice president at Children’s Hospital of Wisconsin. “Our mission is to have the healthiest children in the state, and through this multi-site initiative, we can improve the health of children across the nation.”The five-year grant comes from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health. Additional support is provided by the Centers for Disease Control and Prevention, the National Spina Bifida Patient Registry and the Spina Bifida Association. Source:University of Wisconsin-Milwaukeelast_img read more

New technology replaces the standard way to repair a hole in the

first_imgThis new method eliminates the need for a patient to be placed on blood thinners as they do when a device is implanted in the heart.Noble Stitch is considered a no footprint procedure, which means that it’s minimally invasive, using a catheter to place a stitch to close the hole and leaving nothing behind. Using the new method also reduces complications that can arise from an implanted metal device, such as the risk for blood clots or irregular heartbeats.”Dr. Clifford Kavinsky, professor of interventional cardiology and cardiovascular disease at Rush Reviewed by James Ives, M.Psych. (Editor)Jun 21 2019Rush University Medical Center is the first hospital in Chicago to use a new technology that enables specially trained physicians to use a single stitch to close an opening between the upper chambers of the heart -; a condition that is found in about one in four people, most of whom are unaware of it. Known as Noble Stitch, the new technology replaces the standard way to close this opening in the heart, which uses an implanted metal device that stays within the heart muscle. This opening in the heart, also known as a patent foramen ovale (PFO), remains when the upper heart chambers do not close naturally after a baby is born. The opening allows for blood to bypass the lungs in an unborn fetus until the lungs are exposed to air. After a newborn takes a first breath, the hole usually closes naturally within a few months.”We have found that this opening remains in over 25% of adults. In the overwhelming majority of people it is a benign condition,” said Kavinsky.Related StoriesCancer incidence among children and young adults with congenital heart diseaseCutting around 300 calories a day protects the heart even in svelte adultsWeightlifting is better for the heart than cardioMost people are not aware they have this opening. In some people, particularly the young, small blood clots can cross through this opening and go up to the brain and causes a stroke. In young people who have had a stroke because of this opening, there is a procedure where a catheter is inserted through a small incision in the inner thigh (groin) and then advanced up into the heart, where it is used to insert a device that stitches the opening closed,” said Kavinsky.According to the American Heart Association, more than 1.3 million Americans have some form of congenital heart defect (CHD), with about 40,000 children born with a heart defect each year. The causes of congenital heart defects are unknown.In January 2018, the FDA approved Noble Stitch for use in vascular and cardiovascular procedures in the United States.”The NobleStitch EL, which has been used extensively in Europe and Italy, is an excellent option for patient with PFOs,” said Dr. Joshua Murphy, assistant professor of pediatric cardiology at Rush University Medical Center.When done properly, the stitch provides the best short and long-term outcomes for patients, with essentially a natural, native, atrial tissue.””As a center of excellence for PFO treatment procedures, we are glad to be the first to offer this treatment option to our patients,” said Kavinsky.A study for PFO closure using Noble Stitch will begin at Rush in the fall of 2019. Source:Rush University Medical Centerlast_img read more

What is Kejriwals issue with LG whose role is clearly defined Sheila

first_img SHARE SHARE EMAIL COMMENT Published on Senior Congress leader Sheila Dikshit addresses the media in New Delhi on Friday   –  PTI SHARE June 15, 2018 Former Delhi CMasks incumbent to approach PM for full statehood to Delhi Chief Minister Arvind Kejriwal should first read the Constitution and then approach the Prime Minister and Parliament for full statehood to Delhi, Congress leader Sheila Dikshit said on Friday, criticising the AAP’s ministers for staging a sit-in at the Lieutenant Governor’s office.Dikshit said the role of the Delhi Lt Governor and the Chief Minister is defined in the Constitution and wondered why AAP leaders were protesting at L-G Anil Baijal’s office since Monday. “What is his (Kejriwal’s) intention behind it?”At a press conference, the three-time Delhi chief minister said she feels “ashamed” that a Chief Minister is releasing photos sitting on a protest at the L-G’s office.Contrasting her governance with that of the Aam Aadmi Party, she said the BJP ruled at the Centre when she became the Delhi chief minister in 1998 and there was no conflict between them.She said the Congress also demanded full statehood for Delhi, but it never politicised the issue.She said Kejriwal must understand that Delhi is a Union Territory and he is wrong if he thinks he can have a governance model like Haryana and Uttar Pradesh.“He should first read the Constitution. If he thinks that there is a need to make amendments to the Constitution, he should approach Modiji and Parliament,” she said.Delhi Congress chief Ajay Maken said the AAP and the BJP were doing “dharna politics” as they are “not serious” about public issues such as water shortage. COMMENTSlast_img read more