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Experts welcome Indonesia’s vow to share H5N1 data

first_imgMay 19, 2008 (CIDRAP News) – Indonesia’s recent announcement that it would immediately begin sharing H5N1 avian influenza genetic sequences with a new public database is being hailed by experts as a promising development, though there is a concern that having actual virus isolates would be better.Indonesia’s decision, announced by Health Minister Siti Fadilah Supari, was detailed in a May 15 report from the Associated Press (AP).In early 2007 Indonesia stopped sharing H5N1 virus samples with the World Health Organization (WHO) to protest what it perceived as a lack of access to costly pandemic vaccines that companies in developed countries produce from the shared samples. The government has shared only a few samples with WHO labs since then.Though Indonesia’s embargo has drawn support from some other developing countries and nongovernmental organizations, the country was widely criticized by global health officials and researchers, who have said sample sharing is crucial for tracking the evolution of the virus and developing treatments and vaccines.”We have always promoted the sharing of influenza data, all we ask for is that it be done in a fair, transparent, and equitable manner,” Supari said of Indonesia’s decision to contribute sequence data to the new database, known as the Global Initiative on Sharing Avian Influenza Data (GISAID), according to the AP report.A WHO working group has met several times to resolve the virus-sharing dispute, but has made little progress. The issue is expected to surface at the annual World Health Assembly, which started today in Geneva. However, the working group’s next formal meeting is scheduled for November.Benefits, limitations of sequence dataTwo researchers who work with H5N1 viruses say they are pleased that Indonesia, which leads the world in human H5N1 cases and deaths, will share the genetic sequences from their virus samples. However, their opinions varied on how useful the genetic sequences will be without the actual H5N1 virus isolates, which are used to make seed strains for vaccines.Richard Webby, PhD, a virologist at St Jude Children’s Research Hospital in Memphis, Tenn., told CIDRAP News that the sequences would allow researchers to track virus evolution.”It is absolutely a step in the right direction, and it allows everyone to see how the Indonesian viruses are evolving genetically,” Webby said. “Unfortunately, however, our ability to accurately predict antigenic and biologic properties from sequence data alone is embarrassingly poor. So, no, it [providing genetic sequence data] is not as good as sharing viruses.”Webby added that the most important aspect scientists can determine from a viral isolate that they can’t learn from a sequence is antigenicity—how well a virus will cross-react with antibodies generated against other strains. “Antigenic relatedness, not genetic relatedness, is key to vaccine strain selection,” he said.Also, sequence data alone can’t predict the transmission and pathogenicity changes that researchers depend on to make risk assessments, Webby said.Adolfo Garcia-Sastre, PhD, a virologist at Mount Sinai School of Medicine in New York City, also welcomed the news about Indonesia sharing its viral sequences and voiced a more optimistic view on their usefulness.”Sequences are very important to understand antigenicity, and even if no viruses are shared, provide the basis to make reagents to experimentally test antigenicity and pathogenicity,” he told CIDRAP News. Garcia-Sastre is also principal investigator for the Center for Research on Influenza Pathogenesis, one of six National Institute for Allergy and Infectious Diseases Centers of Excellence for Influenza Research and Surveillance.GISAID launches data-sharing platformThe idea for the GISAID database was generated by a group of 70 scientists and health officials who signed a letter in the August 31, 2006, issue of Nature proposing the formation of a new consortium to promote greater sharing of H5N1 genetic sequences.Aside from concerns about potential social inequities, virus-sharing has been a flashpoint for other controversies, including intellectual property rights and published credits for virus sources in scientific papers.Supari had earlier signaled Indonesia’s support for the GISAID database when she announced its initial launch in March 2007, according to a Mar 28, 2007, GISAID press release. Her support for the GISAID database followed a technical meeting on the virus-sharing issue that was attended by health ministers of countries that have been hit by the H5N1 virus, GISAID’s statement said.An official with GISAID, who asked not to be named, told CIDRAP News that the database’s platform for sharing H5N1 genetic sequences went live on May 15. The official confirmed that Indonesia has committed to sharing its virus data and is currently uploading its sequences into the GISAID EpiFlu database. China, Russia, and other nations are also in the process of submitting sequences, the GISAID source said.”This global health research community will find that the GISAID platform provides a high standard of data and analysis tools that uniquely promotes responsible sharing of information,” Supari said in the 2007 press release.GISAID said the public can freely access the database, which includes both human and animal H5N1 sequences, after they register and agree to share and credit the use of others’ data, analyze findings jointly, publish results collaboratively, and refrain from pressing intellectual property rights issues that relate to diagnostic, drug, and vaccine developments.When the plan to form GISAID was announced in 2006, one of the global health officials who signed the Nature letter was Dr. Nancy Cox, head of the Influenza Division at the US Centers for Disease Control and Prevention (CDC). Cox had told CIDRAP News that the GISAID database would be very useful because it would be linked with clinical and epidemiological data.The efforts of Peter Bogner, GISAID director, were instrumental in garnering the support of Supari and other officials, the AP reported. Bogner is a former broadcast executive who became involved in virus-sharing issues after attending a World Economic Forum in Switzerland 2 years ago, the report said.See also:Aug 25, 2006, CIDRAP News story “Scientists launch effort to share avian flu data”GISAID Web sitehttp://www.gisaid.org/WHO World Health Assembly agenda and proceedingslast_img read more

Europa League: Inter now unstoppable – Conte

first_img Loading… “I’m happy for him, as he deserves all of this, but Romelu must also thank the team for putting him in the conditions to express himself in the best form of his entire career.” Inter have certainly improved in recent months at the way they play it out from the back. “We do a lot of work on this in training. If you find a team that presses you high up the pitch, there are memorised positional situations that give players the chance to escape that pressing. It’s all about vertical passes and finding space. “I hear people call playing out from the back a counter-attack, but that’s not the case. You start deep and create the space left behind those defenders. “We did well to press Bayer and cause them huge problems playing the ball. At the same time, we did well to find the right solutions. Samir Handanovic is very good at seeing those options for the pass and finding the free man.” read also:Champions League: Suarez rates Barca vs Bayern contest 50-50 The coach was asked if he’ll be happier watching this game back for the performance or angrier at the number of wasted scoring opportunities? “I can’t be angry tonight, I can only congratulate these lads on all they’ve done in Serie A, throughout the season and now in the Europa League. We’ll show the team back some situations, both positive and ones we can improve, but the video lectures aren’t about finding blame, but rather showing how to improve next time.” Inter are already qualified for the Champions League, but winning the Europa League would bump them up from third to first seeds in the draw for the group stage. FacebookTwitterWhatsAppEmail分享 Antonio Conte said Inter ‘want to go all the way’ in the Europa League after beating Bayer Leverkusen 2-1 in the quarter-final. ‘We never let them play the ball comfortably.’ They will face either Shakhtar Donetsk or FC Basel in the semi-final on August 17, Inter’s first major semi-final since winning the Treble in 2010. Nicolò Barella and Romelu Lukaku had given them a 2-0 lead early doors, but Kai Havertz made it anxious until the end, even if the Nerazzurri wasted so many chances. They also had two penalties awarded only to be revoked via VAR, so the 2-1 scoreline does not reflect this performance. “We are very satisfied because it was a very good performance. We prepared it the right way, never let Leverkusen play the ball comfortably, we did what we worked on in training,” the coach told Sky Sport Italia. “As I always end up saying, we could’ve killed the game off earlier and relaxed a little. We didn’t allow many chances at all, but the fact is we had so many chances and should’ve scored more than two. “The lads showed how hungry they were, how determined to prove that what they’re doing is important. We’ve got an opportunity to play a Europa League semi-final, so can be pleased, but from tomorrow must begin preparing for the semi-final. “We want to achieve the maximum. We want to go all the way.” Lukaku can’t stop scoring, as he set a new all-time record by finding the net in nine consecutive Europa League games, while it was his 31st competitive goal of the season for Inter. “It’s difficult to talk about individuals when you have such a great team performance. Romelu is having an excellent season, supported by the team, who put everyone in a position to express themselves at their best on an individual level too.center_img Promoted ContentYou’ve Only Seen Such Colorful Hairdos In A Handful Of Anime7 Worst Things To Do To Your Phone7 Things That Actually Ruin Your PhoneThe Very Last Bitcoin Will Be Mined Around 2140. Read More2020 Tattoo Trends: Here’s What You’ll See This Year10 Phones That Can Work For Weeks Without RechargingWho Is The Most Powerful Woman On Earth?Best & Worst Celebrity Endorsed Games Ever MadeThese TV Characters Proved That Any 2 People Can Bury The HatchetThis Guy Photoshopped Himself Into Celeb Pics And It’s Hysterical10 Phones That Can Easily Fit In The Smallest Pocket5 Of The World’s Most Unique Theme Parkslast_img read more

Second forum for Cowley County Wellington campus proposal is tonight at 6 p.m.

first_imgby Tracy McCue, Sumner Newscow — About 50 people attended the Sumner County Economic Development Commission Cowley College  Town Hall meetings this morning at 10:00 a.m. If you missed the first one, a second one will be held at 6 p.m. tonight. These meetings will be held at the Wellington High School Auditorium, located at 1700 East 16th in Wellington.Dr. Dennis Rittle, President, Cowley College, is providing a presentation and respond to questions regarding Cowley College’s plan for a college campus in Sumner County. Please plan to attend either one of these meetings.There will be a petition to sign if you are interested in showing your support. More details regarding the petition to come later.Follow us on Facebook.Follow us on Twitter. Close Forgot password? Please put in your email: Send me my password! Close message Login This blog post All blog posts Subscribe to this blog post’s comments through… RSS Feed Subscribe via email Subscribe Subscribe to this blog’s comments through… RSS Feed Subscribe via email Subscribe Follow the discussion Comments (2) Logging you in… Close Login to IntenseDebate Or create an account Username or Email: Password: Forgot login? Cancel Login Close WordPress.com Username or Email: Password: Lost your password? Cancel Login Dashboard | Edit profile | Logout Logged in as Admin Options Disable comments for this page Save Settings Sort by: Date Rating Last Activity Loading comments… You are about to flag this comment as being inappropriate. Please explain why you are flagging this comment in the text box below and submit your report. The blog admin will be notified. Thank you for your input. +4 Vote up Vote down Cammy McComb · 210 weeks ago Dr. Rittle did a very good job of informing the public. I believe we need Cowley College in Wellington to boost our economy! Please get out there tonight and find out more! Report Reply 0 replies · active 210 weeks ago +3 Vote up Vote down southsideresident · 210 weeks ago Yes, I too support Cowley College in Wellington, a good investment. However, until the hospital and schools are more secure financially by the expansion of Medicaid to pay for uncompensated care and a better plan for the school it’s like putting the cart before the horse. CC would help train students for jobs. Any industry or business has as one of it’s two priorities good schools and good health care plus recreational facilities. We have our schools funded for another year but after that ???? . Our governor and legislature opposed expansion of Medicaid that would put our hospital be on better financial footing. Vote for Don Shimkus for KS Senate Dist. #32, Michelle Schiltz, for KS House Dist. #80, Jo Roitman, for KS House Dist. #116. Check them out before the Nov. election. They will support expansion of Medicaid and adequate funding of our public schools. Report Reply 0 replies · active 210 weeks ago Post a new comment Enter text right here! Comment as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Submit Comment Subscribe to None Replies All new comments Comments by IntenseDebate Enter text right here! Reply as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Cancel Submit Comment Subscribe to None Replies All new commentslast_img read more